Description

Job Description

Vertex Cell and Gene Therapies (VCGT) is seeking an energetic and self-motivated Scientist I to join its growing Delivery R&D team. The full-time role will support research in the development, optimization and evaluation of therapeutics delivered via biomedical devices. The Formulation Chemist Scientist I will be responsible for developing and evaluating novel polymeric formulations by executing study protocols, reports, and specifications specific to cell and gene therapy modalities. The successful candidate will have a balanced understanding of the biomedical device field, including the characterization of polymers. The position is located in Providence, RI and will report to the Senior Manager, Translational Engineering.

Activities

• Extensive hands-on experience in the development of novel polymeric formulations/technologies
• Conduct material properties evaluations including mechanical testing, FTIR, DSC, SEM, TGA, etc. and various assays for functional characterization
• Evaluate in vitro (ELISA, HPLC) and in vivo release kinetics (oral, IP, IV, SQ routes) of proteins and small molecules
• Analyze and evaluate novel coating formulations based on polymers / biomaterials or biomaterials containing surface modifications
• Collate and interpret complex analytical data systematically, and compiles results into a cohesive body of conclusions or recommendations to guide project decisions
• Exercises solid judgment and demonstrates ability to handle multiple activities for a study
• Performs advanced and/or complex experimental troubleshooting
• Identifies, prioritizes and introduces relevant emerging analytical technologies or approaches
• Maintains accurate laboratory notebooks with inclusion of or references to sources of raw data
• Independently prepares presentations and presents experimental conclusions at internal project team meetings

• Effectively communicate with all levels of the organization and promote and contribute to a cohesive team working culture
• Ability to work on several projects simultaneously as well as participate on cross-functional teams.

Required qualifications:

• PhD with 0-3 years of experience in Life Sciences, Polymer Chemistry, Materials Science, Biology, or related, or the equivalent combination of education and experience
• Experience in the development of polymeric controlled release drug delivery systems
• Demonstrated knowledge in polymer and materials characterization
• Strong interpersonal and team skills
• Ability to communicate effectively
• The ability to work in a fast pace environment, manage priorities, and maintain timelines for multiple activities
• Ability to quantify experimental results and present to groups effectively
• Flexibility in working schedule to accommodate weekend work
• Proficiency in MS Word, Excel, PowerPoint, and knowledge of statistics.

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Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.