Description

Job Description

Vertex Pharmaceuticals is seeking a highly motivated protein chemist with expertise in integral membrane proteins, and a track record of generating high-quality recombinant protein for structural biology, biochemistry and biophysics experiments.

Key Responsibilities:

Expression, purification, and characterization of integral membrane proteins for structural biology and biophysical experiments.

Expertise in designing and implementing protein purification protocols to generate high quality, homogeneous protein, using various chromatography methods such as affinity, size exclusion, ion exchange.

Pro-actively troubleshoot the expression and purification of challenging targets to ensure consistent deliveries of high-quality protein.

Characterization of the stability and homogeneity of purified proteins using techniques such as FPLC, HPLC, SDS-PAGE, LC-MS.

An open mindset and willingness to learn new techniques as needed to support the Protein Sciences group is desirable.

Requirements

Bachelor's or Master's degree in biochemistry, molecular biology, or a related field and a minimum of 2 years' experience in a research laboratory. Industry experience is highly desired.

Proven record and expertise in molecular biology and protein chemistry techniques.

Demonstrated ability to produce and analyze data and communicate them effectively.

Team oriented, with the ability to work effectively in a fast-paced, timeline-driven work environment.

Excellent organizational and documentational practices.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Please note that Vertex requires COVID-19 vaccination for all employees working in the U.S. as a condition of employment at Vertex, subject to medical, religious or other accommodations or exemptions required by law. We believe this requirement is vital to keeping everyone at Vertex and in our communities safe. This requirement applies to both existing and new employees who may at any time work on-site at a Vertex facility or visit another location on behalf of Vertex (e.g., conferences, customer visits, etc.), including all remote employees. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition atApplicationAssistance@vrtx.com.